有機合成百題精解

第一章 解答有機合成題的基礎(chǔ)知識準備················································································ 1
一、烴類和簡單雜環(huán)的官能團化····························································································· 1
二、官能團的轉(zhuǎn)換················································································································ 6
三、復(fù)習(xí)和熟練掌握碳鏈的增長方法······················································································ 9
四、熟悉一些重要的重排反應(yīng)······························································································ 10
五、掌握碳碳鍵的構(gòu)建方法·································································································· 10
六、掌握化學(xué)鍵的切斷與逆合成分析法················································································· 10
七、熟悉按照化學(xué)鍵異裂方式切斷后的常見合成子及其對應(yīng)的等價物······································· 10
八、逆合成分析切斷法的技巧······························································································ 11
九、一條理想的合成路線的確定需要把握的幾點···································································· 11
第二章 有機化合物常見增長和縮短碳鏈的方法····································································· 12
第一節(jié) 增長碳鏈的方法····································································································· 12
一、增加一個碳原子的常見方法··························································································· 12
二、增加兩個碳原子的常見方法··························································································· 16
三、增加三個碳原子的常見方法··························································································· 19
四、增加四個碳原子的常見方法··························································································· 22
五、碳鏈倍增法·················································································································· 22
第二節(jié) 縮短碳鏈的方法····································································································· 24
一、減少一個碳原子的常見方法··························································································· 24
二、烯烴通過氧化斷鍵減少一個或多個碳的方法···································································· 25
第三章 有機合成練習(xí)題題解······························································································· 26
參考文獻·························································································································· 238