生物信息學(xué)

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作　者：	英D.R.Westhead等著
出版社：	科學(xué)出版社
叢編項(xiàng)：	精要速覽系列先鋒版
標(biāo)　簽：	醫(yī)用生物學(xué)

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ISBN：	9787030110251	出版時(shí)間：	2003-01-01	包裝：	平裝
開(kāi)本：	24cm	頁(yè)數(shù)：	257頁(yè)	字?jǐn)?shù)：

內(nèi)容簡(jiǎn)介

　　“精要速覽系列（InstantNotesSeries）”是國(guó)外教材“BestSeller”榜的上榜教材。該系列結(jié)構(gòu)新穎，視角獨(dú)特；重點(diǎn)明確，脈絡(luò)分明；圖表簡(jiǎn)明清晰；英文自然易懂，被國(guó)內(nèi)多所重點(diǎn)院校選用作為雙語(yǔ)教材。先鋒版是繼“現(xiàn)代生物學(xué)精要速覽”之后推出的跨學(xué)科的升級(jí)版本。本書(shū)是該系列中的《生物信息學(xué)》分冊(cè)，全書(shū)共15章，全面系統(tǒng)地概括了該學(xué)科的核心內(nèi)容和前沿動(dòng)態(tài)，涉及生物學(xué)數(shù)據(jù)的獲得與處理、系統(tǒng)發(fā)生學(xué)、芯片數(shù)據(jù)分析、蛋白質(zhì)組數(shù)據(jù)分析、生物信息學(xué)的應(yīng)用等主要內(nèi)容。本書(shū)是指導(dǎo)大學(xué)生快速掌握生物信息學(xué)基礎(chǔ)知識(shí)的優(yōu)秀教材，也是輔助教師授課的極佳教學(xué)參考書(shū)，同時(shí)可供生命科學(xué)相關(guān)專(zhuān)業(yè)的研究生參考。

作者簡(jiǎn)介

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圖書(shū)目錄

Abbreviations
Preface
SectionA-Overviewofbioinformatics
A1Thescoeofbioinformatics
A2BioinformaticsandtheInternet
A3UsefulbioinformaticssitesontheWWW
SectionB-Dataacquisition
B1SequencingDNA,RNAandproteins
B2Determinationofproteinstructure
B3Geneandproteinexpressiondata
B4Proteininteractiondata
SectionC-Databases-contents,structureandannotation
C1Fileformats
C2Annotatedsequencedatabases
C3Genomeandorganism-specificdatabases
C4Miscellaneousdatabases
SectionD-Retrievalofbiologicaldata
D1DataretrievalwithEntrezandDBGET/LinkDB
D2DataretrievalwithSRS(sequenceretrievalsystem)
SectionE-Searchingsequencedatabasesbysequence
E1Sequencesimilaritysearches
E2Aminoacidsubstitutionmatrices
E3Databasessearches:FASTAandBLAST
E4Sequencefilters
E5IterativedatabasesearchesandPSI-BLAST
SectionF-Multiplesequencealignmentandfamilyrelationships
F1Multiplesequencealignmentandfamilyrelationships
F2Proteinfamiliesandpatterndatabases
F3Proteindomainfamilies
SectionG-Phylogenetics
G1Phylogenetics,cladisticsandontology
G2Buildingphylogenetictrees
G3Evolutionofmacromolecularsequences
SectionH-Sequenceannotation
H1Principlesofgenomeannotation
H2Annotationtoolsandresources
SectionI-Structuralbioinformatics
I1Conceptualmodelsofproteinstructure
I2Therelationshipofproteinthree-dimensionalstructuretoproteinfunction
I3Theevolutionofproteinstructureandfunction
I4Obtaining,viewingandanalyzingstructuraldata
I5Structuralalignment
I6Classificationofproteinsofknownthree-dimensionalstructure:CATHandSCOP
I7Introductiontoproteinstructureprediction
I8Structurepredictionbycomparativemodeling
I9Secondarystructureprediction
I10Adnancedproteinstructurepredictionandpredictionstrategies
SectionJ-Microarraydataanalysis
J1Microarraydata:analysismethods
J2Microarraydata:toolsandresources
J3SequencesamplingandSAGE
SectionK-Proteomicdataanalysis
K1Analyzingdatafrom2D-PAGEgels
K2Analyzingproteinmassspectrometrydata
SectionL-Higher-ordersystems
L1Modelingandreconstructingmolecularpathways
L2Proteininteractioninformatics
L3Higher-ordermodels
SectionM-Cheminformaticsinbiology
M1Conventionsforrepresentingmolecularpathways
M2Cheminformaticsresources
SectionN-Bioinformaticsinthepharmaceuticalindustry
N1Bioinformaticsanddrugdiscovery
N2Pharmainformaticsresources
SectionO-Basicprinciplesofcomputinginbioinformatics
O1Runningcomputersoftware
O2Computeroperatingsystems
O3Softwaredownloadingandinstallation
O4Databasemanagement
Furtherreading
Glossary
Index